About Safety

Juvéderm™ injectable gel is a dermal filler made from hyaluronic acid—a naturally occurring substance in your skin. Juvéderm™ is the first FDA-approved hyaluronic acid dermal filler that has demonstrated its safety and effectiveness in persons of color.

Before you decide on treatment with Juvéderm™ injectable gel, you'll want to find an experienced healthcare professional—someone who is familiar with the injection process. Find an experienced doctor in your area.

Talking to your healthcare professional about treatment with Juvéderm™

If you're considering treatment with Juvéderm™ injectable gel, your healthcare professional should ask about your medical history to determine if you are an appropriate candidate for treatment. Juvéderm™ injectable gel should not be used in patients who have:

• Severe allergies marked by a history of anaphylaxis or presence of multiple severe allergies
• A history of allergies to gram-positive bacterial proteins

Your healthcare professional should also warn you that the safety and effectiveness of Juvéderm™ injectable gel for the treatment of areas other than facial wrinkles and folds (such as lips) have not been established in controlled clinical studies.

In addition, you and your healthcare professional should discuss the following important treatment considerations in order to help avoid unsatisfactory results and complications:

• Patients who are using substances that can prolong bleeding, such as aspirin or ibuprofen, as with any injection, may experience increased bruising or bleeding at the injection site. You should inform your healthcare professional before treatment if you are using these types of substances.
• If laser treatment, chemical peeling, or any other procedure based on active dermal response is considered after treatment with Juvéderm™ injectable gel, there is a possible risk of an inflammatory reaction at the treatment site.
• Juvéderm™ injectable gel should be used with caution in patients on immunosuppressive therapy, or therapy used to decrease the body's immune response, as there may be an increased risk of infection.
• The safety of Juvéderm™ injectable gel for use during pregnancy, in breastfeeding females, or in patients under 18 years has not been established.
• The safety of Juvéderm™ in patients with a history of excessive scarring (eg, hypertrophic scarring and keloid formations) and pigmentation disorders has not been studied.

Other treatment options to consider

Other treatments for dermal soft tissue augmentation include bovine-based collagen and other hyaluronic acid-based dermal fillers. Aside from these treatments, additional options for the correction of lines and wrinkles do exist, including facial creams, BOTOX® Cosmetic (botulinum toxin type A), chemical peels, and laser skin surface treatments, and may be discussed with your healthcare professional.

Learn more about the side effects of Juvéderm.